Guideline Acceptable Troponin I
Imprecision level of ≤10% at the 99th percentile of the normal population
Cardiac troponin I measurements can be used as an aid in the diagnosis of acute myocardial infarction (AMI). Cardiac troponin I can also be used as an aid in the risk stratification of patients with acute coronary syndromes (ACS) with respect to their relative risk of mortality. Given the impressive levels of myocardial specificity and sensitivity, the ESC/ACC Joint Committee has recognized troponin as the preferred biochemical marker for myocardial damage and redefined acute myocardial infarction (AMI), in part, as a rise and gradual fall of troponin levels.1
1Thygesen, K et al, Euro Heart J. (2012) 33, 2551-2567.